Chemicals and Drugs

Flutamide

An antiandrogen with about the same potency as cyproterone in rodent and canine species.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antiandrogen with about the same potency as cyproterone in rodent and canine species.

Chemical Identity

Chemical Information

Molecular Formula
C11H11F3N2O3
Molecular Weight
276.21 g/mol
CAS Registry No.
13311-84-7
IUPAC Name
2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
InChIKey
MKXKFYHWDHIYRV-UHFFFAOYSA-N
SMILES
CC(C)C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F
MeSH Unique ID
D005485
Source
PubChem CID 3397

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

41 entry terms
  • Niftolid
  • Niftolide
  • Apimid
  • Apo-Flutamide
  • Chimax
  • Cytamid
  • Drogenil
  • Euflex
  • Eulexin
  • Eulexine
  • Fluken
  • Flulem
  • Flumid
  • Fluta 1A Pharma
  • Fluta-GRY
  • Fluta-cell
  • Flutamin
  • Flutandrona
  • Flutaplex
  • Flutexin
  • Fugerel
  • Grisetin
  • Novo-Flutamide
  • Oncosal
  • PMS-Flutamide
  • Prostacur
  • Prostica
  • Prostogenat
  • SCH-13521
  • Testotard
  • Apo Flutamide
  • ApoFlutamide
  • Fluta GRY
  • Fluta cell
  • FlutaGRY
  • Flutacell
  • Novo Flutamide
  • NovoFlutamide
  • PMS Flutamide
  • SCH 13521
  • SCH13521

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under ANILIDES 1975-90

MeSH Record

Previous Indexing

  • Anilides (1973-1974)
  • Hydrocarbons, Fluorinated (1974)
  • Nitro Compounds (1973-1974)

MeSH Hierarchy

Tree Numbers

  1. D02w.065w.199w.420w
  2. D02w.092w.146.113w.420w

AMA Style

References

  1. National Library of Medicine. Flutamide. Medical Subject Headings (MeSH). 2026. Unique ID D005485. http://id.nlm.nih.gov/mesh/2026/D005485
  2. Flutamide. In: Wikipedia. https://en.wikipedia.org/wiki/Flutamide
  3. Flutamide. In: Wikidata. https://www.wikidata.org/wiki/Q418669
  4. Flutamide. In: PubChem Compound. CID 3397. https://pubchem.ncbi.nlm.nih.gov/compound/3397