Structured Summary
Abstract
An indole-heptanoic acid derivative that inhibits HMG COA REDUCTASE and is used to treat HYPERCHOLESTEROLEMIA. In contrast to other statins, it does not appear to interact with other drugs that inhibit CYP3A4.
Chemical Identity
Chemical Information
- Molecular Formula
- C24H26FNO4
- Molecular Weight
- 411.5 g/mol
- CAS Registry No.
- 155229-75-7
- IUPAC Name
- (E,3R,5S)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid
- InChIKey
- FJLGEFLZQAZZCD-MCBHFWOFSA-N
- SMILES
- CC(C)N1C2=CC=CC=C2C(=C1/C=C/[C@H](C[C@H](CC(=O)O)O)O)C3=CC=C(C=C3)F
- MeSH Unique ID
- D000077340
- Source
- PubChem CID 446155
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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MeSH Record
Synonyms
10 entry terms
- 7-(3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl)-3,5-dihydroxy-6-heptenoate
- Fluindostatin
- Fluvastatin Sodium
- Fluvastatin Sodium Salt
- Lescol
- XU 62-320
- XU 62320
- XU-62320
- XU 62 320
- XU62320
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
2019 (1990)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Fluvastatin. Medical Subject Headings (MeSH). 2026. Unique ID D000077340. http://id.nlm.nih.gov/mesh/2026/D000077340
- Fluvastatin. In: Wikipedia. https://en.wikipedia.org/wiki/Fluvastatin
- Fluvastatin. In: Wikidata. https://www.wikidata.org/wiki/Q417942
- Fluvastatin. In: PubChem Compound. CID 446155. https://pubchem.ncbi.nlm.nih.gov/compound/446155