Structured Summary
Abstract
An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of the ACTIN CYTOSKELETON terminate and attach to the transmembrane linkers, INTEGRINS, which in turn attach through their extracellular domains to EXTRACELLULAR MATRIX PROTEINS.
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Synonyms
18 entry terms
- Adhesion Plaques
- Cell-Matrix Adherens Junctions
- Focal Contacts
- Adherens Junction, Cell-Matrix
- Adherens Junctions, Cell-Matrix
- Adhesion Plaque
- Adhesion, Focal
- Adhesions, Focal
- Cell Matrix Adherens Junctions
- Cell-Matrix Adherens Junction
- Contact, Focal
- Contacts, Focal
- Focal Adhesion
- Focal Contact
- Junction, Cell-Matrix Adherens
- Junctions, Cell-Matrix Adherens
- Plaque, Adhesion
- Plaques, Adhesion
MeSH Record
Aspects Covered
15 allowable subheadings
Indexed with the subheadings chemistry, classification, drug effects, enzymology, genetics, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.
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History Note
2001
MeSH Record
Previous Indexing
- Cell Adhesion (1986-2000)
- Extracellular Matrix (1986-2000)
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. Focal Adhesions. Medical Subject Headings (MeSH). 2026. Unique ID D022001. http://id.nlm.nih.gov/mesh/2026/D022001
- Focal Adhesions. In: Wikipedia. https://en.wikipedia.org/wiki/Focal_adhesion
- Focal Adhesions. In: Wikidata. https://www.wikidata.org/wiki/Q904514