Diseases

Focal Segmental Glomerulosclerosis

A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

15 entry terms
  • Glomerulonephritis, Focal Sclerosing
  • Glomerulosclerosis, Focal
  • Glomerulosclerosis, Focal Segmental
  • Focal Glomerulosclerosis
  • Focal Sclerosing Glomerulonephritides
  • Focal Sclerosing Glomerulonephritis
  • Glomerulonephritides, Focal Sclerosing
  • Sclerosing Glomerulonephritides, Focal
  • Sclerosing Glomerulonephritis, Focal
  • Segmental Glomerulosclerosis, Focal
  • Hyalinosis, Segmental
  • Hyalinosis, Segmental Glomerular
  • Segmental Glomerular Hyalinosis
  • Glomerular Hyalinosis, Segmental
  • Segmental Hyalinosis

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2007 (1977)

MeSH Record

Previous Indexing

  • Kidney Glomerulus (1966-1976)

MeSH Hierarchy

Tree Numbers

  1. C12.050.351.968w.419w.570w.363w.640w
  2. C12.200.777w.419w.570w.363w.660w
  3. C12.950w.419w.570w.363w.640w

AMA Style

References

  1. National Library of Medicine. Focal Segmental Glomerulosclerosis. Medical Subject Headings (MeSH). 2026. Unique ID D005923. http://id.nlm.nih.gov/mesh/2026/D005923
  2. Focal Segmental Glomerulosclerosis. In: Wikipedia. https://en.wikipedia.org/wiki/Focal_segmental_glomerulosclerosis
  3. Focal Segmental Glomerulosclerosis. In: Wikidata. https://www.wikidata.org/wiki/Q1435223