Chemicals and Drugs

Formins

A family of multidomain microfilament proteins associated with ACTIN FILAMENTS. They generally have multiple Formin-Homology domains (e.g., FH2 domain) and additionally have a RhoGTPase-binding domain and a diaphanous inhibitory domain. Formins and homologs are involved in actin reorganization.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of multidomain microfilament proteins associated with ACTIN FILAMENTS. They generally have multiple Formin-Homology domains (e.g., FH2 domain) and additionally have a RhoGTPase-binding domain and a diaphanous inhibitory domain. Formins and homologs are involved in actin reorganization.

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Classification

Broader headings

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MeSH Record

Synonyms

15 entry terms
  • FMN Proteins
  • Formin
  • Formin Homology Proteins
  • DIAPH Protein 1
  • DIAPH Protein 2
  • DIAPH Proteins
  • Diaphanous-Related Formin Homology Proteins
  • Diaphanous-Related Formins
  • FMN Protein 1
  • FMN Protein 2
  • Formin 1 Protein
  • Formin 2 Protein
  • Diaphanous Related Formin Homology Proteins
  • Diaphanous Related Formins
  • Formins, Diaphanous-Related

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2020

MeSH Record

Previous Indexing

  • Microfilament Proteins (1992-2019)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Formins. Medical Subject Headings (MeSH). 2026. Unique ID D000080865. http://id.nlm.nih.gov/mesh/2026/D000080865
  2. Formins. In: Wikipedia. https://en.wikipedia.org/wiki/Formins
  3. Formins. In: Wikidata. https://www.wikidata.org/wiki/Q5470213