Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Freeze Substitution

A modification of the freeze-drying method in which the ice within the frozen tissue is replaced by alcohol or other solvent at a very low temperature.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A modification of the freeze-drying method in which the ice within the frozen tissue is replaced by alcohol or other solvent at a very low temperature.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

1 entry terms
  • Substitution, Freeze

MeSH Record

Aspects Covered

10 allowable subheadings

Indexed with the subheadings classification, economics, ethics, history, instrumentation, methods, standards, statistics & numerical data, trends, veterinary.

MeSH Record

Indexing Annotation

in freeze drying, replacement of ice by alcohol or other solvent

MeSH Record

History Note

93

MeSH Record

Previous Indexing

  • Cryopreservation (1989-1992)
  • Freeze Drying (1977-1992)
  • Freezing (1966-1992)

MeSH Hierarchy

Tree Numbers

  1. E01w.370.225.500.620.760.160w.260w.270
  2. E01w.370.225.750.600.760.160w.260w.270
  3. E02w.792.156w.260w.270
  4. E05.200.500.620.760.160w.260w.270
  5. E05.200.750.600.760.160w.260w.270
  6. E05.760.156w.260w.270

AMA Style

References

  1. National Library of Medicine. Freeze Substitution. Medical Subject Headings (MeSH). 2026. Unique ID D017110. http://id.nlm.nih.gov/mesh/2026/D017110
  2. Freeze Substitution. In: Wikidata. https://www.wikidata.org/wiki/Q73522610