Chemicals and Drugs

Fusaric Acid

A picolinic acid derivative isolated from various Fusarium species. It has been proposed for a variety of therapeutic applications but is primarily used as a research tool. Its mechanisms of action are poorly understood. It probably inhibits DOPAMINE BETA-HYDROXYLASE, the enzyme that converts dopamine to norepinephrine. It may also have other actions, including the inhibition of cell proliferation and DNA synthesis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A picolinic acid derivative isolated from various Fusarium species. It has been proposed for a variety of therapeutic applications but is primarily used as a research tool. Its mechanisms of action are poorly understood. It probably inhibits DOPAMINE BETA-HYDROXYLASE, the enzyme that converts dopamine to norepinephrine. It may also have other actions, including the inhibition of cell proliferation and DNA synthesis.

Chemical Identity

Chemical Information

Molecular Formula
C10H13NO2
Molecular Weight
179.22 g/mol
CAS Registry No.
536-69-6
IUPAC Name
5-butylpyridine-2-carboxylic acid
InChIKey
DGMPVYSXXIOGJY-UHFFFAOYSA-N
SMILES
CCCCC1=CN=C(C=C1)C(=O)O
MeSH Unique ID
D005669
Source
PubChem CID 3442

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

6 entry terms
  • 5-Butyl-2-pyridinedicarboxylic Acid
  • 5 Butyl 2 pyridinedicarboxylic Acid
  • Acid, 5-Butyl-2-pyridinedicarboxylic
  • Acid, Fusaric
  • Calcium Fusarate
  • Fusarate, Calcium

MeSH Record

Aspects Covered

27 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

/biosyn permitted if by organism

MeSH Record

History Note

91(75); was see under PICOLINIC ACIDS 1975-90

MeSH Record

Previous Indexing

  • Picolinic Acids (1969-1974)

MeSH Hierarchy

Tree Numbers

  1. D03w.066.707.200w
  2. D03w.383.725w.705.200w

AMA Style

References

  1. National Library of Medicine. Fusaric Acid. Medical Subject Headings (MeSH). 2026. Unique ID D005669. http://id.nlm.nih.gov/mesh/2026/D005669
  2. Fusaric Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Fusaric_acid
  3. Fusaric Acid. In: Wikidata. https://www.wikidata.org/wiki/Q905703
  4. Fusaric Acid. In: PubChem Compound. CID 3442. https://pubchem.ncbi.nlm.nih.gov/compound/3442