Chemicals and Drugs

Fusidic Acid

An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed). It acts by inhibiting translocation during protein synthesis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed). It acts by inhibiting translocation during protein synthesis.

Chemical Identity

Chemical Information

Molecular Formula
C31H48O6
Molecular Weight
516.7 g/mol
CAS Registry No.
6990-06-3
IUPAC Name
(2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoic acid
InChIKey
IECPWNUMDGFDKC-MZJAQBGESA-N
SMILES
C[C@H]1[C@@H]2CC[C@]3([C@H]([C@]2(CC[C@H]1O)C)[C@@H](C[C@@H]\4[C@@]3(C[C@@H](/C4=C(/CCC=C(C)C)\C(=O)O)OC(=O)C)C)O)C
MeSH Unique ID
D005672
Source
PubChem CID 3000226

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Acid, Fusidic
  • Fucithalmic
  • Fusidate Sodium
  • Fusidic Acid, Sodium Salt
  • Fusidin
  • Silver Fusidate
  • Sodium Fusidate
  • Stanicide
  • Fusidate, Silver
  • Fusidate, Sodium
  • Sodium, Fusidate

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

65; FUSIDIN was see FUSIDIC ACID 1965-95

MeSH Hierarchy

Tree Numbers

  1. D04w.210.500w.247.222w.222.347.389w
  2. D04w.210.500w.247.808w.489w
  3. D10w.570w.938w.515w

AMA Style

References

  1. National Library of Medicine. Fusidic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D005672. http://id.nlm.nih.gov/mesh/2026/D005672
  2. Fusidic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Fusidic_acid
  3. Fusidic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q259930
  4. Fusidic Acid. In: PubChem Compound. CID 3000226. https://pubchem.ncbi.nlm.nih.gov/compound/3000226