Phenomena and Processes

G-Quadruplexes

Higher-order DNA and RNA structures formed from guanine-rich sequences. They are formed around a core of at least 2 stacked tetrads of hydrogen-bonded GUANINE bases. They can be formed from one two or four separate strands of DNA (or RNA) and can display a wide variety of topologies, which are a consequence of various combinations of strand direction, length, and sequence. (From Nucleic Acids Res. 2006;34(19):5402-15)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Higher-order DNA and RNA structures formed from guanine-rich sequences. They are formed around a core of at least 2 stacked tetrads of hydrogen-bonded GUANINE bases. They can be formed from one two or four separate strands of DNA (or RNA) and can display a wide variety of topologies, which are a consequence of various combinations of strand direction, length, and sequence. (From Nucleic Acids Res. 2006;34(19):5402-15)

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Synonyms

25 entry terms
  • Guanine-Quadruplexes
  • G Quadruplexes
  • Guanine Quadruplexes
  • DNA G-Quadruplexes
  • DNA, Quadruplex
  • G-Quadruplexes, DNA
  • G-Quadruplexes, RNA
  • Guanine-Quartets
  • Guanine-Tetrads
  • Quadruplex DNA
  • RNA, G-Quadruplexes
  • Tetraplex DNA
  • DNA G Quadruplexes
  • DNA, Tetraplex
  • G Quadruplexes, DNA
  • G Quadruplexes, RNA
  • G-Quadruplexes RNA
  • G-Quadruplexes RNAs
  • Guanine Quartets
  • Guanine Tetrads
  • Guanine-Quartet
  • Guanine-Tetrad
  • RNA G-Quadruplexes
  • RNA, G Quadruplexes
  • RNAs, G-Quadruplexes

MeSH Record

Aspects Covered

2 allowable subheadings

Indexed with the subheadings drug effects, radiation effects.

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History Note

2008 (1994)

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AMA Style

References

  1. National Library of Medicine. G-Quadruplexes. Medical Subject Headings (MeSH). 2026. Unique ID D054856. http://id.nlm.nih.gov/mesh/2026/D054856
  2. G-Quadruplexes. In: Wikipedia. https://en.wikipedia.org/wiki/G-quadruplex
  3. G-Quadruplexes. In: Wikidata. https://www.wikidata.org/wiki/Q411641