Chemicals and Drugs

GAP-43 Protein

A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.

MeSH Record

Classification

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MeSH Record

Synonyms

14 entry terms
  • B-50 Protein
  • GAP-43
  • GAP43 Protein
  • Growth-Associated Protein 43
  • Nerve Growth Cone Membrane Protein GAP-43
  • Neuromodulin
  • Phosphoprotein B-50
  • Phosphoprotein F1
  • Phosphoprotein pp46
  • B 50 Protein
  • GAP 43 Protein
  • Growth Associated Protein 43
  • Nerve Growth Cone Membrane Protein GAP 43
  • Phosphoprotein B 50

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

98; use GAP-43 PROTEIN (NM) 1986-97

MeSH Record

Previous Indexing

  • Calmodulin-Binding Proteins (1986-1992)
  • Membrane Glycoproteins (1988-1997)
  • Membrane Proteins (1986-1989)
  • Nerve Tissue Proteins (1986-1997)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. GAP-43 Protein. Medical Subject Headings (MeSH). 2026. Unique ID D019922. http://id.nlm.nih.gov/mesh/2026/D019922
  2. GAP-43 Protein. In: Wikidata. https://www.wikidata.org/wiki/Q24741523