Chemicals and Drugs

G Protein-Coupled Inwardly-Rectifying Potassium Channels

A family of inwardly-rectifying potassium channels that are activated by PERTUSSIS TOXIN sensitive G-PROTEIN-COUPLED RECEPTORS. GIRK potassium channels are primarily activated by the complex of GTP-BINDING PROTEIN BETA SUBUNITS and GTP-BINDING PROTEIN GAMMA SUBUNITS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of inwardly-rectifying potassium channels that are activated by PERTUSSIS TOXIN sensitive G-PROTEIN-COUPLED RECEPTORS. GIRK potassium channels are primarily activated by the complex of GTP-BINDING PROTEIN BETA SUBUNITS and GTP-BINDING PROTEIN GAMMA SUBUNITS.

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Classification

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MeSH Record

Synonyms

31 entry terms
  • G Protein-Activated Potassium Channels
  • GIRK Potassium Channels
  • Kir3 Potassium Channels
  • G Protein Activated Potassium Channels
  • G Protein Coupled Inwardly Rectifying Potassium Channels
  • Potassium Channels, GIRK
  • Potassium Channels, Kir3
  • G Protein-Coupled Inwardly-Rectifying Potassium Channel 1
  • G Protein-Coupled Inwardly-Rectifying Potassium Channel 2
  • G Protein-Coupled Inwardly-Rectifying Potassium Channel 3
  • G Protein-Coupled Inwardly-Rectifying Potassium Channel 4
  • GIRK1 Potassium Channel
  • GIRK2 Potassium Channel
  • GIRK3 Potassium Channel
  • GIRK4 Potassium Channel
  • Kir3.1 Potassium Channel
  • Kir3.2 Potassium Channel
  • Kir3.3 Potassium Channel
  • Kir3.4 Potassium Channel
  • G Protein Coupled Inwardly Rectifying Potassium Channel 1
  • G Protein Coupled Inwardly Rectifying Potassium Channel 2
  • G Protein Coupled Inwardly Rectifying Potassium Channel 3
  • G Protein Coupled Inwardly Rectifying Potassium Channel 4
  • Potassium Channel, GIRK1
  • Potassium Channel, GIRK2
  • Potassium Channel, GIRK3
  • Potassium Channel, GIRK4
  • Potassium Channel, Kir3.1
  • Potassium Channel, Kir3.2
  • Potassium Channel, Kir3.3
  • Potassium Channel, Kir3.4

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1993)

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AMA Style

References

  1. National Library of Medicine. G Protein-Coupled Inwardly-Rectifying Potassium Channels. Medical Subject Headings (MeSH). 2026. Unique ID D051676. http://id.nlm.nih.gov/mesh/2026/D051676
  2. G Protein-Coupled Inwardly-Rectifying Potassium Channels. In: Wikipedia. https://en.wikipedia.org/wiki/G_protein-coupled_inwardly_rectifying_potassium_channel
  3. G Protein-Coupled Inwardly-Rectifying Potassium Channels. In: Wikidata. https://www.wikidata.org/wiki/Q3001168