Chemicals and Drugs

Ganglionic Blockers

Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.

MeSH Record

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Broader headings

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Synonyms

8 entry terms
  • Blocking Agents, Ganglionic
  • Ganglionic Blockaders
  • Ganglionic Blocking Agents
  • Ganglioplegic Agents
  • Agents, Ganglionic Blocking
  • Agents, Ganglioplegic
  • Blockaders, Ganglionic
  • Blockers, Ganglionic

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

95; was GANGLIONIC BLOCKADERS 1970-94; was GANGLIONIC-BLOCKING AGENTS 1963-69

MeSH Hierarchy

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MeSH Record

NLM Classification

QV 132

AMA Style

References

  1. National Library of Medicine. Ganglionic Blockers. Medical Subject Headings (MeSH). 2026. Unique ID D005730. http://id.nlm.nih.gov/mesh/2026/D005730
  2. Ganglionic Blockers. In: Wikidata. https://www.wikidata.org/wiki/Q50430017