Chemicals and Drugs

Gap Junction alpha-5 Protein

A GAP JUNCTION alpha subunit containing four transmembrane domains expressed in the atrial myocardium and ventricular HEART CONDUCTION SYSTEM including PURKINJE FIBERS. Mutations in the human gene GJA5 are associated with cardiac conduction abnormalities such as a familial ATRIAL FIBRILLATION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A GAP JUNCTION alpha subunit containing four transmembrane domains expressed in the atrial myocardium and ventricular HEART CONDUCTION SYSTEM including PURKINJE FIBERS. Mutations in the human gene GJA5 are associated with cardiac conduction abnormalities such as a familial ATRIAL FIBRILLATION.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

8 entry terms
  • Connexin 40
  • Connexin 40 Protein
  • GJA5 Protein
  • Gap Junction A5
  • Gap Junction alpha5 Protein
  • Gap Junction alpha 5 Protein
  • Protein, Connexin 40
  • Protein, GJA5

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2024(2010)

MeSH Hierarchy

Tree Number

  1. D12.776w.543w.585w.250w.400

AMA Style

References

  1. National Library of Medicine. Gap Junction alpha-5 Protein. Medical Subject Headings (MeSH). 2026. Unique ID D000097003. http://id.nlm.nih.gov/mesh/2026/D000097003
  2. Gap Junction alpha-5 Protein. In: Wikidata. https://www.wikidata.org/wiki/Q24745256