Chemicals and Drugs

Gemifloxacin

A naphthyridine and fluoroquinolone derivative antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used for the treatment of community-acquired pneumonia and acute bacterial infections associated with chronic bronchitis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A naphthyridine and fluoroquinolone derivative antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used for the treatment of community-acquired pneumonia and acute bacterial infections associated with chronic bronchitis.

Chemical Identity

Chemical Information

Molecular Formula
C18H20FN5O4
Molecular Weight
389.4 g/mol
CAS Registry No.
175463-14-6
IUPAC Name
7-[(4Z)-3-(aminomethyl)-4-methoxyiminopyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
InChIKey
ZRCVYEYHRGVLOC-HYARGMPZSA-N
SMILES
CO/N=C/1\CN(CC1CN)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F
MeSH Unique ID
D000077735
Source
PubChem CID 9571107

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • 7-(3-aminomethyl-4-methoxyimino-pyrrolidine-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-(1,8)-naphthyridine-3-carboxylic acid
  • Factive
  • Gemifloxacin Mesylate
  • LB 20304
  • LB-20304
  • LB20304
  • SB 265805
  • SB-265805
  • SB265805

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2019 (1997)

MeSH Hierarchy

Tree Numbers

  1. D03w.633.100.612.250w
  2. D03w.633.100.810.835.830w.250.322w

AMA Style

References

  1. National Library of Medicine. Gemifloxacin. Medical Subject Headings (MeSH). 2026. Unique ID D000077735. http://id.nlm.nih.gov/mesh/2026/D000077735
  2. Gemifloxacin. In: Wikipedia. https://en.wikipedia.org/wiki/Gemifloxacin
  3. Gemifloxacin. In: Wikidata. https://www.wikidata.org/wiki/Q1639595
  4. Gemifloxacin. In: PubChem Compound. CID 9571107. https://pubchem.ncbi.nlm.nih.gov/compound/9571107