Phenomena and Processes

Gene Fusion

The GENETIC RECOMBINATION of the parts of two or more GENES resulting in a gene with different or additional regulatory regions, or a new chimeric gene product. ONCOGENE FUSION includes an ONCOGENE as at least one of the fusion partners and such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS. ARTIFICIAL GENE FUSION is carried out in vitro by RECOMBINANT DNA technology.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The GENETIC RECOMBINATION of the parts of two or more GENES resulting in a gene with different or additional regulatory regions, or a new chimeric gene product. ONCOGENE FUSION includes an ONCOGENE as at least one of the fusion partners and such gene fusions are often detected in neoplastic cells and are transcribed into ONCOGENE FUSION PROTEINS. ARTIFICIAL GENE FUSION is carried out in vitro by RECOMBINANT DNA technology.

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Synonyms

3 entry terms
  • Fusion, Gene
  • Fusions, Gene
  • Gene Fusions

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Aspects Covered

6 allowable subheadings

Indexed with the subheadings drug effects, ethics, genetics, immunology, physiology, radiation effects.

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Indexing Annotation

ARTIFICIAL GENE FUSION is also available

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History Note

2006

MeSH Record

Previous Indexing

  • Artificial Gene Fusion (1998-2005)

MeSH Hierarchy

Tree Number

  1. G05.728w.385

AMA Style

References

  1. National Library of Medicine. Gene Fusion. Medical Subject Headings (MeSH). 2026. Unique ID D050939. http://id.nlm.nih.gov/mesh/2026/D050939
  2. Gene Fusion. In: Wikidata. https://www.wikidata.org/wiki/Q42866962