Phenomena and Processes

Genetic Epigenesis

A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.

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Synonyms

7 entry terms
  • Epigenesis, Genetic
  • Epigenetic Process
  • Epigenetic Processes
  • Epigenetics Processes
  • Process, Epigenetic
  • Processes, Epigenetic
  • Processes, Epigenetics

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2004

MeSH Hierarchy

Tree Number

  1. G05.308w.203

MeSH Record

NLM Classification

QU 476

AMA Style

References

  1. National Library of Medicine. Genetic Epigenesis. Medical Subject Headings (MeSH). 2026. Unique ID D044127. http://id.nlm.nih.gov/mesh/2026/D044127
  2. Genetic Epigenesis. In: Wikidata. https://www.wikidata.org/wiki/Q64443099