Chemicals and Drugs

Glutathione

A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.

Chemical Identity

Chemical Information

Molecular Formula
C10H17N3O6S
Molecular Weight
307.33 g/mol
CAS Registry No.
70-18-8
IUPAC Name
(2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
InChIKey
RWSXRVCMGQZWBV-WDSKDSINSA-N
SMILES
C(CC(=O)N[C@@H](CS)C(=O)NCC(=O)O)[C@@H](C(=O)O)N
MeSH Unique ID
D005978
Source
PubChem CID 124886

MeSH Record

Classification

Broader headings

Narrower headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

6 entry terms
  • gamma-L-Glu-L-Cys-Gly
  • gamma-L-Glutamyl-L-Cysteinylglycine
  • gamma L Glu L Cys Gly
  • gamma L Glutamyl L Cysteinylglycine
  • Reduced Glutathione
  • Glutathione, Reduced

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Hierarchy

Tree Number

  1. D12.644w.456w.448w

MeSH Record

NLM Classification

QU 68

AMA Style

References

  1. National Library of Medicine. Glutathione. Medical Subject Headings (MeSH). 2026. Unique ID D005978. http://id.nlm.nih.gov/mesh/2026/D005978
  2. Glutathione. In: Wikipedia. https://en.wikipedia.org/wiki/Glutathione
  3. Glutathione. In: Wikidata. https://www.wikidata.org/wiki/Q116907
  4. Glutathione. In: PubChem Compound. CID 124886. https://pubchem.ncbi.nlm.nih.gov/compound/124886