Chemicals and Drugs

Glyburide

An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide

Chemical Identity

Chemical Information

Molecular Formula
C23H28ClN3O5S
Molecular Weight
494.0 g/mol
CAS Registry No.
10238-21-8
IUPAC Name
5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
InChIKey
ZNNLBTZKUZBEKO-UHFFFAOYSA-N
SMILES
COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
MeSH Unique ID
D005905
Source
PubChem CID 3488

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

15 entry terms
  • Glibenclamide
  • Glybenclamide
  • Daonil
  • Diabeta
  • Euglucon 5
  • Euglucon N
  • HB-419
  • HB-420
  • Maninil
  • Micronase
  • Neogluconin
  • HB 419
  • HB 420
  • HB419
  • HB420

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

92; was GLIBENCLAMIDE 1971-91 (Prov 1971-72); GLYBURIDE was see GLIBENCLAMIDE 1973-91

MeSH Record

Previous Indexing

  • Hypoglycemic Agents (1966-1970)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Glyburide. Medical Subject Headings (MeSH). 2026. Unique ID D005905. http://id.nlm.nih.gov/mesh/2026/D005905
  2. Glyburide. In: Wikipedia. https://en.wikipedia.org/wiki/Glibenclamide
  3. Glyburide. In: Wikidata. https://www.wikidata.org/wiki/Q420626
  4. Glyburide. In: PubChem Compound. CID 3488. https://pubchem.ncbi.nlm.nih.gov/compound/3488