Diseases

Gonadal Dysgenesis

A number of syndromes with defective gonadal developments such as streak GONADS and dysgenetic testes or ovaries. The spectrum of gonadal and sexual abnormalities is reflected in their varied sex chromosome (SEX CHROMOSOMES) constitution as shown by the karyotypes of 45,X monosomy (TURNER SYNDROME); 46,XX (GONADAL DYSGENESIS, 46XX); 46,XY (GONADAL DYSGENESIS, 46,XY); and sex chromosome MOSAICISM; (GONADAL DYSGENESIS, MIXED). Their phenotypes range from female, through ambiguous, to male. This concept includes gonadal agenesis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A number of syndromes with defective gonadal developments such as streak GONADS and dysgenetic testes or ovaries. The spectrum of gonadal and sexual abnormalities is reflected in their varied sex chromosome (SEX CHROMOSOMES) constitution as shown by the karyotypes of 45,X monosomy (TURNER SYNDROME); 46,XX (GONADAL DYSGENESIS, 46XX); 46,XY (GONADAL DYSGENESIS, 46,XY); and sex chromosome MOSAICISM; (GONADAL DYSGENESIS, MIXED). Their phenotypes range from female, through ambiguous, to male. This concept includes gonadal agenesis.

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MeSH Record

Synonyms

2 entry terms
  • Dysgenesis, Gonadal
  • Gonadal Agenesis

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

80; was see TURNER'S SYNDROME 1967-79

MeSH Record

Previous Indexing

  • Sex Differentiation Disorders (1966-1979)
  • Turner Syndrome (1967-1979)

MeSH Hierarchy

Tree Numbers

  1. C12.050.351.875w.253w.309w
  2. C12.200.706w.316w.309w
  3. C12.800w.316w.309w
  4. C16w.131w.939w.316w.309w
  5. C19w.391.119w.309w

MeSH Record

NLM Classification

QS 677

AMA Style

References

  1. National Library of Medicine. Gonadal Dysgenesis. Medical Subject Headings (MeSH). 2026. Unique ID D006059. http://id.nlm.nih.gov/mesh/2026/D006059
  2. Gonadal Dysgenesis. In: Wikipedia. https://en.wikipedia.org/wiki/Gonadal_dysgenesis
  3. Gonadal Dysgenesis. In: Wikidata. https://www.wikidata.org/wiki/Q1332427