Structured Summary
Abstract
A DNA-binding orphan nuclear receptor that negatively regulates expression of ARNTL TRANSCRIPTION FACTORS and plays a role as a regulatory component of the circadian clock system. The Nr1d1 nuclear receptor expression is cyclically-regulated by a feedback loop involving its positive regulation by CLOCK PROTEIN; BMAL1 PROTEIN heterodimers and its negative regulation by CRYPTOCHROME and PERIOD PROTEINS.
MeSH Record
Classification
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MeSH Record
Synonyms
9 entry terms
- Nuclear Receptor NR1D1
- Nuclear Receptor Subfamily 1, Group D, Member 1
- Rev-erb-alpha Nuclear Receptors
- V-erbA-Related Protein EAR-1
- NR1D1, Nuclear Receptor
- Nuclear Receptors, Rev-erb-alpha
- Receptor NR1D1, Nuclear
- Rev erb alpha Nuclear Receptors
- V erbA Related Protein EAR 1
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2010
MeSH Record
Previous Indexing
- DNA-Binding Proteins (1990-2009)
- Receptors, Cytoplasmic and Nuclear (1990-2009)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Group D Member 1 Nuclear Receptor Subfamily 1. Medical Subject Headings (MeSH). 2026. Unique ID D056953. http://id.nlm.nih.gov/mesh/2026/D056953
- Group D Member 1 Nuclear Receptor Subfamily 1. In: Wikidata. https://www.wikidata.org/wiki/Q15323346