Chemicals and Drugs

Group IV Phospholipases A2

A cytosolic phospholipase A2 group that plays an important role in the release of free ARACHIDONIC ACID, which in turn is metabolized to PROSTAGLANDINS by the CYCLOOXYGENASE pathway and to LEUKOTRIENES by the 5-LIPOXYGENASE pathway.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cytosolic phospholipase A2 group that plays an important role in the release of free ARACHIDONIC ACID, which in turn is metabolized to PROSTAGLANDINS by the CYCLOOXYGENASE pathway and to LEUKOTRIENES by the 5-LIPOXYGENASE pathway.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

39 entry terms
  • Group IV Cytosolic Phospholipase A2
  • PLA(2)-IV
  • PLA2-IV
  • Phospholipase A2 IV
  • Phospholipases A2, Group IV
  • Cytosolic Phospholipase A2 alpha
  • Cytosolic Phospholipase A2 beta
  • Cytosolic Phospholipase A2 delta
  • Cytosolic Phospholipase A2 epsilon
  • Cytosolic Phospholipase A2 gamma
  • Group IVA Phospholipase A2
  • Group IVA Phospholipases A2
  • Group IVB Phospholipase A2
  • Group IVB Phospholipases A2
  • Group IVC Phospholipase A2
  • Group IVC Phospholipases A2
  • Group IVD Phospholipase A2
  • Group IVD Phospholipases A2
  • Group IVE Phospholipase A2
  • Group IVE Phospholipases A2
  • Group IVF Phospholipase A2
  • Group IVF Phospholipases A2
  • Phospholipase A(2)alpha
  • Phospholipase A2 Group IVA
  • Phospholipase A2, Group IVB
  • Phospholipase A2, Group IVC
  • Phospholipase A2, Group IVD
  • Phospholipase A2, Group IVE
  • Phospholipase A2, Group IVF
  • Phospholipase A2-alpha
  • Phospholipase A2-beta
  • Phospholipase A2-gamma
  • cPLA2-alpha
  • cPLA2-gamma
  • Phospholipase A2 alpha
  • Phospholipase A2 beta
  • Phospholipase A2 gamma
  • cPLA2 alpha
  • cPLA2 gamma

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

/antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS

MeSH Record

History Note

2008(1997)

MeSH Hierarchy

Tree Number

  1. D08.811w.277w.352w.100.680w.750.937w.625.249

AMA Style

References

  1. National Library of Medicine. Group IV Phospholipases A2. Medical Subject Headings (MeSH). 2026. Unique ID D054513. http://id.nlm.nih.gov/mesh/2026/D054513
  2. Group IV Phospholipases A2. In: Wikidata. https://www.wikidata.org/wiki/Q78112981