Chemicals and Drugs

Growth Arrest-Specific Protein 6

A ligand for RECEPTOR PROTEIN-TYROSINE KINASES AXL, TYRO3 and MERTK through which it regulates cell growth and survival of ENDOTHELIAL CELLS; CELL ADHESION; and CELL MIGRATION. GAS6 also has critical roles in the development of NATURAL KILLER CELLS and PLATELET ACTIVATION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A ligand for RECEPTOR PROTEIN-TYROSINE KINASES AXL, TYRO3 and MERTK through which it regulates cell growth and survival of ENDOTHELIAL CELLS; CELL ADHESION; and CELL MIGRATION. GAS6 also has critical roles in the development of NATURAL KILLER CELLS and PLATELET ACTIVATION.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

2 entry terms
  • GAS6 Protein
  • Growth-Potentiating Factor, 70-kDa

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2026 (1993)

MeSH Hierarchy

Tree Numbers

  1. D12.644w.276.648w
  2. D12.776w.467.648w
  3. D23.529.648w

AMA Style

References

  1. National Library of Medicine. Growth Arrest-Specific Protein 6. Medical Subject Headings (MeSH). 2026. Unique ID D000099255. http://id.nlm.nih.gov/mesh/2026/D000099255
  2. Growth Arrest-Specific Protein 6. In: Wikipedia. https://en.wikipedia.org/wiki/GAS6
  3. Growth Arrest-Specific Protein 6. In: Wikidata. https://www.wikidata.org/wiki/Q21110911