Chemicals and Drugs

Guanabenz

An alpha-2 selective adrenergic agonist used as an antihypertensive agent.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An alpha-2 selective adrenergic agonist used as an antihypertensive agent.

Chemical Identity

Chemical Information

Molecular Formula
C8H8Cl2N4
Molecular Weight
231.08 g/mol
CAS Registry No.
5051-62-7
IUPAC Name
2-[(E)-(2,6-dichlorophenyl)methylideneamino]guanidine
InChIKey
WDZVGELJXXEGPV-YIXHJXPBSA-N
SMILES
C1=CC(=C(C(=C1)Cl)/C=N/N=C(N)N)Cl
MeSH Unique ID
D006143
Source
PubChem CID 5702063

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

17 entry terms
  • 2,6-Dichlorobenzylideneaminoguanidine
  • 2,6 Dichlorobenzylideneaminoguanidine
  • BR-750
  • Guanabenz Acetate
  • Guanabenz Monoacetate
  • WY-8678
  • Wyeth-Ayerst of Guanabenz Acetate
  • Wytensin
  • Acetate Wyeth-Ayerst, Guanabenz
  • Acetate, Guanabenz
  • BR 750
  • BR750
  • Guanabenz Acetate Wyeth-Ayerst
  • Monoacetate, Guanabenz
  • WY 8678
  • WY8678
  • Wyeth Ayerst of Guanabenz Acetate

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under GUANIDINES 1975-90

MeSH Record

Previous Indexing

  • Guanidines (1973-1974)
  • Imines (1973-1974)

MeSH Hierarchy

Tree Number

  1. D02w.078w.370.435w

AMA Style

References

  1. National Library of Medicine. Guanabenz. Medical Subject Headings (MeSH). 2026. Unique ID D006143. http://id.nlm.nih.gov/mesh/2026/D006143
  2. Guanabenz. In: Wikipedia. https://en.wikipedia.org/wiki/Guanabenz
  3. Guanabenz. In: Wikidata. https://www.wikidata.org/wiki/Q5613542
  4. Guanabenz. In: PubChem Compound. CID 5702063. https://pubchem.ncbi.nlm.nih.gov/compound/5702063