Chemicals and Drugs

Guanfacine

A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.

Chemical Identity

Chemical Information

Molecular Formula
C9H9Cl2N3O
Molecular Weight
246.09 g/mol
CAS Registry No.
29110-47-2
IUPAC Name
N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide
InChIKey
INJOMKTZOLKMBF-UHFFFAOYSA-N
SMILES
C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl
MeSH Unique ID
D016316
Source
PubChem CID 3519

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

10 entry terms
  • BS-100-141
  • Estulic
  • Guanfacine Hydrochloride
  • Guanfacine Monohydrochloride
  • Lon798
  • Tenex
  • BS 100 141
  • BS100141
  • Hydrochloride, Guanfacine
  • Monohydrochloride, Guanfacine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91

MeSH Record

Previous Indexing

  • Adrenergic alpha Agonists (1969-1990)
  • Antihypertensive Agents (1966-1990)
  • Guanidines (1966-1990)
  • Phenylacetates (1966-1990)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Guanfacine. Medical Subject Headings (MeSH). 2026. Unique ID D016316. http://id.nlm.nih.gov/mesh/2026/D016316
  2. Guanfacine. In: Wikipedia. https://en.wikipedia.org/wiki/Guanfacine
  3. Guanfacine. In: Wikidata. https://www.wikidata.org/wiki/Q5613599
  4. Guanfacine. In: PubChem Compound. CID 3519. https://pubchem.ncbi.nlm.nih.gov/compound/3519