Structured Summary
Abstract
Guanosine 5'-diphosphate 2'(3')-diphosphate. A guanine nucleotide containing four phosphate groups. Two phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids are not available for protein synthesis. Synonym: magic spot I.
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Classification
Broader headings
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Synonyms
13 entry terms
- Alarmone ppGpp
- Bacterial Magic Spot ppGpp
- Guanosine 3'-Diphosphate 5'-Diphosphate
- Guanosine 5'-(trihydrogen diphosphate), mono(trihydrogen diphosphate) (ester)
- Guanosine 5'-Diphosphate 3'-Diphosphate
- Guanosine 5'-diphosphate 2'(3')-diphosphate
- ppGpp
- 3'-Diphosphate 5'-Diphosphate, Guanosine
- 5'-Diphosphate 3'-Diphosphate, Guanosine
- Guanosine 3' Diphosphate 5' Diphosphate
- Guanosine 5' Diphosphate 3' Diphosphate
- Tetraphosphate, Guanosine
- ppGpp, Alarmone
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(78); was see under GUANINE NUCLEOTIDES 1978-90
MeSH Record
Previous Indexing
- Guanine Nucleotides (1966-1977)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Guanosine Tetraphosphate. Medical Subject Headings (MeSH). 2026. Unique ID D006159. http://id.nlm.nih.gov/mesh/2026/D006159
- Guanosine Tetraphosphate. In: Wikidata. https://www.wikidata.org/wiki/Q76817993