Organisms

H5N8 Subtype Influenza A Virus

A subtype of INFLUENZA A VIRUS that is highly virulent in poultry and wild birds, but shows varying degrees of pathogenicity in mice. The H5N8 virus subtype has a polybasic amino acid motif at the HA cleavage site which explains its pathogenicity in birds, and expresses surface proteins HEMAGGLUTININ 5 and NEURAMINIDASE 8 which are typical of Highly Pathogenic Avian Influenza viruses.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A subtype of INFLUENZA A VIRUS that is highly virulent in poultry and wild birds, but shows varying degrees of pathogenicity in mice. The H5N8 virus subtype has a polybasic amino acid motif at the HA cleavage site which explains its pathogenicity in birds, and expresses surface proteins HEMAGGLUTININ 5 and NEURAMINIDASE 8 which are typical of Highly Pathogenic Avian Influenza viruses.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

12 entry terms
  • Avian Influenza A(H5N8) Virus
  • H5N8
  • H5N8 Bird Flu Virus
  • H5N8 Influenza Virus
  • H5N8 Virus
  • H5N8 subtype
  • Influenza A Virus, H5N8 Subtype
  • Influenza A(H5N8) Virus
  • H5N8 Viruses
  • H5N8 subtypes
  • Virus, H5N8
  • subtype, H5N8

MeSH Record

Aspects Covered

13 allowable subheadings

Indexed with the subheadings chemistry, classification, drug effects, enzymology, genetics, growth & development, immunology, isolation & purification, metabolism, pathogenicity, physiology, radiation effects, ultrastructure.

MeSH Record

Indexing Annotation

infection: coordinate with INFLUENZA, HUMAN in humans, or INFLUENZA IN BIRDS in birds, or ORTHOMYXOVIRIDAE INFECTIONS in other animals

MeSH Record

History Note

2017

MeSH Record

Previous Indexing

  • Influenza A virus (2013-2016)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. H5N8 Subtype Influenza A Virus. Medical Subject Headings (MeSH). 2026. Unique ID D000071225. http://id.nlm.nih.gov/mesh/2026/D000071225
  2. H5N8 Subtype Influenza A Virus. In: Wikipedia. https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H5N8
  3. H5N8 Subtype Influenza A Virus. In: Wikidata. https://www.wikidata.org/wiki/Q6030277