Chemicals and Drugs

HIV Core Protein p24

A major core protein of the human immunodeficiency virus encoded by the HIV gag gene. HIV-seropositive individuals mount a significant immune response to p24 and thus detection of antibodies to p24 is one basis for determining HIV infection by ELISA and Western blot assays. The protein is also being investigated as a potential HIV immunogen in vaccines.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A major core protein of the human immunodeficiency virus encoded by the HIV gag gene. HIV-seropositive individuals mount a significant immune response to p24 and thus detection of antibodies to p24 is one basis for determining HIV infection by ELISA and Western blot assays. The protein is also being investigated as a potential HIV immunogen in vaccines.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

12 entry terms
  • HIV Major Core Protein p24
  • HIV Protein p24
  • HIV gag Gene Product p24
  • HIV p24 Antigen
  • HTLV-III p24
  • gag Protein p24, HIV
  • p24 protein, Human Immunodeficiency Virus
  • p24(HIV)
  • HTLV III p24
  • p24 Antigen, HIV
  • p24, HIV Protein
  • p24, HTLV-III

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

92; was HIV MAJOR CORE PROTEIN P24 (NM) 1987-91

MeSH Record

Previous Indexing

  • Antigens, Viral (1985-1991)
  • Gene Products, gag (1989-1991)
  • HIV Antigens (1988-1991)
  • Retroviridae Proteins (1985-1991)
  • Viral Core Proteins (1985-1991)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.964w.350.520.300w
  2. D12.776w.964w.775.350.362.500w
  3. D12.776w.964w.775.562.750.500w
  4. D12.776w.964w.970w.600.850.350.362.500w
  5. D23.050w.327.520.300w

AMA Style

References

  1. National Library of Medicine. HIV Core Protein p24. Medical Subject Headings (MeSH). 2026. Unique ID D016655. http://id.nlm.nih.gov/mesh/2026/D016655
  2. HIV Core Protein p24. In: Wikipedia. https://en.wikipedia.org/wiki/P24_capsid_protein
  3. HIV Core Protein p24. In: Wikidata. https://www.wikidata.org/wiki/Q24739702