Anatomy

HL-60 Cells

A promyelocytic cell line derived from a patient with ACUTE PROMYELOCYTIC LEUKEMIA. HL-60 cells lack specific markers for LYMPHOID CELLS but express surface receptors for FC FRAGMENTS and COMPLEMENT SYSTEM PROTEINS. They also exhibit phagocytic activity and responsiveness to chemotactic stimuli. (From Hay et al., American Type Culture Collection, 7th ed, pp127-8)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A promyelocytic cell line derived from a patient with ACUTE PROMYELOCYTIC LEUKEMIA. HL-60 cells lack specific markers for LYMPHOID CELLS but express surface receptors for FC FRAGMENTS and COMPLEMENT SYSTEM PROTEINS. They also exhibit phagocytic activity and responsiveness to chemotactic stimuli. (From Hay et al., American Type Culture Collection, 7th ed, pp127-8)

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

6 entry terms
  • HL60 Cells
  • Cell, HL60
  • Cells, HL60
  • HL 60 Cells
  • HL-60 Cell
  • HL60 Cell

MeSH Record

Aspects Covered

15 allowable subheadings

Indexed with the subheadings chemistry, classification, cytology, drug effects, enzymology, immunology, metabolism, microbiology, parasitology, pathology, physiology, radiation effects, transplantation, ultrastructure, virology.

MeSH Record

Indexing Annotation

almost always NIM with no subheadings; check HUMAN; do not routinely add LEUKEMIA, PROMYELOCYTIC, ACUTE

MeSH Record

History Note

96

MeSH Record

Previous Indexing

  • Cell Line (1979-1995)
  • Tumor Cells, Cultured (1987-1995)

MeSH Hierarchy

Tree Numbers

  1. A11w.251.210w.190.465w
  2. A11w.251.860.180.465w
  3. A11w.627.340w.360.500w

AMA Style

References

  1. National Library of Medicine. HL-60 Cells. Medical Subject Headings (MeSH). 2026. Unique ID D018922. http://id.nlm.nih.gov/mesh/2026/D018922
  2. HL-60 Cells. In: Wikipedia. https://en.wikipedia.org/wiki/HL60
  3. HL-60 Cells. In: Wikidata. https://www.wikidata.org/wiki/Q5630035