Chemicals and Drugs

HLA-D Antigens

Human immune-response or Class II antigens found mainly, but not exclusively, on B-lymphocytes and produced from genes of the HLA-D locus. They are extremely polymorphic families of glycopeptides, each consisting of two chains, alpha and beta. This group of antigens includes the -DR, -DQ and -DP designations, of which HLA-DR is most studied; some of these glycoproteins are associated with certain diseases, possibly of immune etiology.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Human immune-response or Class II antigens found mainly, but not exclusively, on B-lymphocytes and produced from genes of the HLA-D locus. They are extremely polymorphic families of glycopeptides, each consisting of two chains, alpha and beta. This group of antigens includes the -DR, -DQ and -DP designations, of which HLA-DR is most studied; some of these glycoproteins are associated with certain diseases, possibly of immune etiology.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

24 entry terms
  • Antigens, HLA-D
  • Class II Human Antigens
  • HLA-D
  • HLA-Dw
  • HLA-Dw Antigens
  • Human Class II Antigens
  • Ia-Like Antigens, Human
  • Immune Response Associated Antigens, Human
  • Immune Response-Associated Antigens, Human
  • Immune-Associated Antigens, Human
  • Immune-Response Antigens, Human
  • Antigens, HLA D
  • Antigens, HLA-Dw
  • Antigens, Human Ia-Like
  • Antigens, Human Immune-Associated
  • Antigens, Human Immune-Response
  • HLA D Antigens
  • HLA Dw Antigens
  • Human Ia-Like Antigens
  • Human Immune-Associated Antigens
  • Human Immune-Response Antigens
  • Ia Like Antigens, Human
  • Immune Associated Antigens, Human
  • Immune Response Antigens, Human

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

general; prefer specifics

MeSH Record

History Note

87; was see ANTIGENS, IMMUNE RESPONSE 1981-86

MeSH Record

Previous Indexing

  • Antigens, Immune Response (1981-1986)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.509w.400
  2. D12.776w.395w.550w.509w.400
  3. D12.776w.543w.550w.440w.400
  4. D23.050w.301.500.400w.400
  5. D23.050w.301.500.450w.400
  6. D23.050w.705.552.410w.400
  7. D23.050w.705.552.450w.400

AMA Style

References

  1. National Library of Medicine. HLA-D Antigens. Medical Subject Headings (MeSH). 2026. Unique ID D006681. http://id.nlm.nih.gov/mesh/2026/D006681
  2. HLA-D Antigens. In: Wikidata. https://www.wikidata.org/wiki/Q69567835