Diseases

Hairy Cell Leukemia

A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of hairy or flagellated cells in the blood and bone marrow.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of hairy or flagellated cells in the blood and bone marrow.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

7 entry terms
  • Leukemia, Hairy Cell
  • Leukemic Reticuloendotheliosis
  • Reticuloendotheliosis, Leukemic
  • Hairy Cell Leukemias
  • Leukemias, Hairy Cell
  • Leukemic Reticuloendothelioses
  • Reticuloendothelioses, Leukemic

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

since the disease is chronic, do not coordinate with CHRONIC DISEASE; note entry term RETICULOENDOTHELIOSIS, LEUKEMIC;: RETICULOENDOTHELIOSIS, AVIAN is also available

MeSH Record

History Note

78

MeSH Record

Previous Indexing

  • Leukemia (1966-1977)
  • Reticuloendotheliosis (1966-1977)
  • Spleen/pathology (1966-1977)
  • Splenomegaly (1966-1977)

MeSH Hierarchy

Tree Numbers

  1. C04w.557.337w.415w
  2. C15.378w.508w.415w
  3. C15.604w.515w.553w
  4. C20w.683w.515w.517w

MeSH Record

NLM Classification

WH 250

AMA Style

References

  1. National Library of Medicine. Hairy Cell Leukemia. Medical Subject Headings (MeSH). 2026. Unique ID D007943. http://id.nlm.nih.gov/mesh/2026/D007943
  2. Hairy Cell Leukemia. In: Wikipedia. https://en.wikipedia.org/wiki/Hairy_cell_leukemia
  3. Hairy Cell Leukemia. In: Wikidata. https://www.wikidata.org/wiki/Q201299