Diseases

Hand-Foot Syndrome

Chemotherapy-induced dermal side effects that are associated with the use of various CYTOSTATIC AGENTS. Symptoms range from mild ERYTHEMA and/or PARESTHESIA to severe ulcerative dermatitis with debilitating pain involving typically palmoplantar and intertriginous areas. These cutaneous manifestations are sometimes accompanied by nail anomalies.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Chemotherapy-induced dermal side effects that are associated with the use of various CYTOSTATIC AGENTS. Symptoms range from mild ERYTHEMA and/or PARESTHESIA to severe ulcerative dermatitis with debilitating pain involving typically palmoplantar and intertriginous areas. These cutaneous manifestations are sometimes accompanied by nail anomalies.

MeSH Record

Classification

Broader headings

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See Also

MeSH Record

Synonyms

14 entry terms
  • Chemotherapy-Induced Acral Erythema
  • Chemotherapy-Induced Palmoplantar Erythrodysesthesia
  • Acral Erythema, Chemotherapy-Induced
  • Acral Erythemas, Chemotherapy-Induced
  • Chemotherapy Induced Acral Erythema
  • Chemotherapy Induced Palmoplantar Erythrodysesthesia
  • Chemotherapy-Induced Acral Erythemas
  • Chemotherapy-Induced Palmoplantar Erythrodysesthesias
  • Hand Foot Syndrome
  • Hand-Foot Syndromes
  • Palmoplantar Erythrodysesthesia, Chemotherapy-Induced
  • Palmoplantar Erythrodysesthesias, Chemotherapy-Induced
  • Syndrome, Hand-Foot
  • Syndromes, Hand-Foot

MeSH Record

Aspects Covered

34 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

do not confuse with HAND, FOOT AND MOUTH DISEASE

MeSH Record

History Note

2012

MeSH Record

Previous Indexing

  • Foot Dermatoses/chemically induced (1997-2011)
  • Hand Dermatoses/chemically induced (1997-2011)

MeSH Hierarchy

Tree Numbers

  1. C17.800w.174w.600w.587w
  2. C25.100w.468w.380w.587w

AMA Style

References

  1. National Library of Medicine. Hand-Foot Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D060831. http://id.nlm.nih.gov/mesh/2026/D060831
  2. Hand-Foot Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Chemotherapy-induced_acral_erythema
  3. Hand-Foot Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q593277