Chemicals and Drugs

Harmine

Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is one of the active ingredients of hallucinogenic drinks made in the western Amazon region from related plants. It has no therapeutic use, but (as banisterine) was hailed as a cure for postencephalitic PARKINSON DISEASE in the 1920's.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is one of the active ingredients of hallucinogenic drinks made in the western Amazon region from related plants. It has no therapeutic use, but (as banisterine) was hailed as a cure for postencephalitic PARKINSON DISEASE in the 1920's.

Chemical Identity

Chemical Information

Molecular Formula
C13H12N2O
Molecular Weight
212.25 g/mol
CAS Registry No.
442-51-3
IUPAC Name
7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
InChIKey
BXNJHAXVSOCGBA-UHFFFAOYSA-N
SMILES
CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC
MeSH Unique ID
D006247
Source
PubChem CID 5280953

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • 9H-Pyrido(3,4-b)indole, 7-methoxy-1-methyl-
  • Banisterine
  • Leucoharmine
  • Telepathine
  • Yageine

MeSH Record

Aspects Covered

27 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

do not confuse with HARMIDINE or HARMALINE

MeSH Record

History Note

91(75); was see under ALKALOIDS 1975-90

MeSH Record

Previous Indexing

  • Alkaloids (1969-1974)
  • Indoles (1969-1974)
  • Pyridines (1969-1974)

MeSH Hierarchy

Tree Numbers

  1. D03w.132w.436w.384w.500w
  2. D03w.633.100.473.402w.222w.500w
  3. D03w.633.100.496.500.500w.384w.500w
  4. D03w.633.300.154.344w

AMA Style

References

  1. National Library of Medicine. Harmine. Medical Subject Headings (MeSH). 2026. Unique ID D006247. http://id.nlm.nih.gov/mesh/2026/D006247
  2. Harmine. In: Wikipedia. https://en.wikipedia.org/wiki/Harmine
  3. Harmine. In: Wikidata. https://www.wikidata.org/wiki/Q128381
  4. Harmine. In: PubChem Compound. CID 5280953. https://pubchem.ncbi.nlm.nih.gov/compound/5280953