Diseases

Hepatic Encephalopathy

A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

Synonyms

26 entry terms
  • Encephalopathy, Hepatic
  • Encephalopathy, Hepatocerebral
  • Encephalopathy, Portal-Systemic
  • Encephalopathy, Portosystemic
  • Hepatocerebral Encephalopathy
  • Portal-Systemic Encephalopathy
  • Portosystemic Encephalopathy
  • Encephalopathies, Hepatic
  • Encephalopathies, Hepatocerebral
  • Encephalopathies, Portal-Systemic
  • Encephalopathies, Portosystemic
  • Encephalopathy, Portal Systemic
  • Hepatic Encephalopathies
  • Hepatocerebral Encephalopathies
  • Portal Systemic Encephalopathy
  • Portal-Systemic Encephalopathies
  • Portosystemic Encephalopathies
  • Fulminant Hepatic Failure with Cerebral Edema
  • Hepatic Coma
  • Hepatic Stupor
  • Coma, Hepatic
  • Comas, Hepatic
  • Hepatic Comas
  • Hepatic Stupors
  • Stupor, Hepatic
  • Stupors, Hepatic

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

1984; use HEPATIC COMA 1975-83

MeSH Hierarchy

Tree Numbers

  1. C06w.552w.308.500w.356w
  2. C10w.228w.140w.163.360w
  3. C18.452w.132.360w

MeSH Record

NLM Classification

WI 712

AMA Style

References

  1. National Library of Medicine. Hepatic Encephalopathy. Medical Subject Headings (MeSH). 2026. Unique ID D006501. http://id.nlm.nih.gov/mesh/2026/D006501
  2. Hepatic Encephalopathy. In: Wikipedia. https://en.wikipedia.org/wiki/Hepatic_encephalopathy
  3. Hepatic Encephalopathy. In: Wikidata. https://www.wikidata.org/wiki/Q642548