Diseases

Herpes Simplex Encephalitis

An acute (or rarely chronic) inflammatory process of the brain caused by SIMPLEXVIRUS infections which may be fatal. The majority of infections are caused by human herpesvirus 1 (HERPESVIRUS 1, HUMAN) and less often by human herpesvirus 2 (HERPESVIRUS 2, HUMAN). Clinical manifestations include FEVER; HEADACHE; SEIZURES; HALLUCINATIONS; behavioral alterations; APHASIA; hemiparesis; and COMA. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior TEMPORAL LOBE and orbital regions of the FRONTAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, pp751-4)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An acute (or rarely chronic) inflammatory process of the brain caused by SIMPLEXVIRUS infections which may be fatal. The majority of infections are caused by human herpesvirus 1 (HERPESVIRUS 1, HUMAN) and less often by human herpesvirus 2 (HERPESVIRUS 2, HUMAN). Clinical manifestations include FEVER; HEADACHE; SEIZURES; HALLUCINATIONS; behavioral alterations; APHASIA; hemiparesis; and COMA. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior TEMPORAL LOBE and orbital regions of the FRONTAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, pp751-4)

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

20 entry terms
  • Encephalitis, Herpes Simplex
  • Herpes Encephalitis
  • Herpetic Encephalitis
  • Encephalitides, Herpes Simplex
  • Encephalitides, Herpetic
  • Encephalitis, Herpes
  • Encephalitis, Herpetic
  • Herpes Simplex Encephalitides
  • Herpetic Encephalitides
  • Acute Necrotizing Encephalitis, Herpetic
  • Herpes Simplex Meningoencephalitis
  • Herpetic Acute Necrotizing Encephalitis
  • Herpetic Meningoencephalitis
  • Meningoencephalitis, Herpes Simplex Virus
  • Herpes Simplex Meningoencephalitides
  • Herpetic Meningoencephalitides
  • Meningoencephalitides, Herpes Simplex
  • Meningoencephalitides, Herpetic
  • Meningoencephalitis, Herpes Simplex
  • Meningoencephalitis, Herpetic

MeSH Record

Aspects Covered

36 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, transmission, urine, veterinary, virology.

MeSH Record

Indexing Annotation

coord IM with specific SIMPLEXVIRUS if given

MeSH Record

History Note

2000

MeSH Hierarchy

Tree Numbers

  1. C01w.207w.245w.340w.350
  2. C01w.207w.399.750w.350
  3. C01w.925w.182w.525w.350
  4. C01w.925w.256.466.262
  5. C10w.228w.140w.430w.520.750w.350
  6. C10w.228w.228w.245w.340w.350
  7. C10w.228w.228w.399.750w.350
  8. C10w.586.250w.520.750w.350

AMA Style

References

  1. National Library of Medicine. Herpes Simplex Encephalitis. Medical Subject Headings (MeSH). 2026. Unique ID D020803. http://id.nlm.nih.gov/mesh/2026/D020803
  2. Herpes Simplex Encephalitis. In: Wikidata. https://www.wikidata.org/wiki/Q19001292