Chemicals and Drugs

Heterophile Antibodies

Antibodies elicited in a different species from which the antigen originated. These antibodies are directed against a wide variety of interspecies-specific antigens, the best known of which are Forssman, Hanganutziu-Deicher (H-D), and Paul-Bunnell (P-B). Incidence of antibodies to these antigens--i.e., the phenomenon of heterophile antibody response--is useful in the serodiagnosis, pathogenesis, and prognosis of infection and latent infectious states as well as in cancer classification.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Antibodies elicited in a different species from which the antigen originated. These antibodies are directed against a wide variety of interspecies-specific antigens, the best known of which are Forssman, Hanganutziu-Deicher (H-D), and Paul-Bunnell (P-B). Incidence of antibodies to these antigens--i.e., the phenomenon of heterophile antibody response--is useful in the serodiagnosis, pathogenesis, and prognosis of infection and latent infectious states as well as in cancer classification.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

Drug Class

Pharmacological Action

MeSH Record

Synonyms

21 entry terms
  • Antibodies, Heterogenetic
  • Antibodies, Heterologous
  • Antibodies, Heterophil
  • Antibodies, Heterophile
  • Antibodies, Heterotypic
  • Antibodies, Xenogeneic
  • Antibodies, Xenogenic
  • Heteroantibodies
  • Heterogenetic Antibodies
  • Heterologous Antibodies
  • Xenoantibodies
  • Heterophil Antibodies
  • Heterotypic Antibodies
  • Xenogeneic Antibodies
  • Xenogenic Antibodies
  • Forssman Antibody
  • H-D Antibodies
  • Hanganutziu-Deicher Antibodies
  • P-B Antibodies
  • Paul-Bunnell Antibodies
  • Antibody, Forssman

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not coordinate with ANTIBODY FORMATION for /biosyn

MeSH Record

History Note

1987 (1964)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.124w.486.485.114w.191
  2. D12.776w.124w.790.651.114w.191
  3. D12.776w.377w.715.548.114w.191

AMA Style

References

  1. National Library of Medicine. Heterophile Antibodies. Medical Subject Headings (MeSH). 2026. Unique ID D000910. http://id.nlm.nih.gov/mesh/2026/D000910
  2. Heterophile Antibodies. In: Wikidata. https://www.wikidata.org/wiki/Q76122235