Chemicals and Drugs

Hexobendine

A potent vasoactive agent that dilates cerebral and coronary arteries, but slightly constricts femoral arteries, without any effects on heart rate, blood pressure or cardiac output.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A potent vasoactive agent that dilates cerebral and coronary arteries, but slightly constricts femoral arteries, without any effects on heart rate, blood pressure or cardiac output.

Chemical Identity

Chemical Information

Molecular Formula
C30H44N2O10
Molecular Weight
592.7 g/mol
CAS Registry No.
54-03-5
IUPAC Name
3-[methyl-[2-[methyl-[3-(3,4,5-trimethoxybenzoyl)oxypropyl]amino]ethyl]amino]propyl 3,4,5-trimethoxybenzoate
InChIKey
KRQAMFQCSAJCRH-UHFFFAOYSA-N
SMILES
CN(CCCOC(=O)C1=CC(=C(C(=C1)OC)OC)OC)CCN(C)CCCOC(=O)C2=CC(=C(C(=C2)OC)OC)OC
MeSH Unique ID
D006592
Source
PubChem CID 5777

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

3 entry terms
  • Andiamine
  • Ditrimine
  • Ustimon

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under BENZOATES 1975-90

MeSH Record

Previous Indexing

  • Benzoates (1969-1974)
  • Ethylenediamines (1971-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Hexobendine. Medical Subject Headings (MeSH). 2026. Unique ID D006592. http://id.nlm.nih.gov/mesh/2026/D006592
  2. Hexobendine. In: Wikipedia. https://en.wikipedia.org/wiki/Hexobendine
  3. Hexobendine. In: Wikidata. https://www.wikidata.org/wiki/Q12745373
  4. Hexobendine. In: PubChem Compound. CID 5777. https://pubchem.ncbi.nlm.nih.gov/compound/5777