Structured Summary
Abstract
A complex of antigenic proteins obtained from the brush border of kidney tubules. It contains two principal components LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-2 and LDL-RECEPTOR RELATED PROTEIN-ASSOCIATED PROTEIN. The name of this complex is derived from researcher, Dr. Walter Heymann, who developed an experimental model of membranous glomerulonephritis (GLOMERULONEPHRITIS) by injecting this antigenic complex into rats to induce an autoimmune response.
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Synonyms
9 entry terms
- Heymann's Antigen
- Nephritis Antigen, Heyman
- Nephritogenic Antigen
- Receptor-Associated Protein, Heymann Nephritis
- Heyman Nephritis Antigen
- Heymann Antigen
- Heymanns Antigen
- Receptor Associated Protein, Heymann Nephritis
- Fx1A Renal Tubular Antigen
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Aspects Covered
23 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.
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Indexing Annotation
HEYMANN NEPHRITIS ANTIGEN GP330 see LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-2 is also available
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History Note
2002; use HEYMANN NEPHRITIS ANTIGENIC COMPLEX (NM) 1983-2001
MeSH Record
Previous Indexing
- Antigens, Surface (1986-1988)
- Membrane Glycoproteins (1989-2001)
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References
- National Library of Medicine. Heymann Nephritis Antigenic Complex. Medical Subject Headings (MeSH). 2026. Unique ID D026541. http://id.nlm.nih.gov/mesh/2026/D026541
- Heymann Nephritis Antigenic Complex. In: Wikidata. https://www.wikidata.org/wiki/Q77028034