Chemicals and Drugs

Histidinol

The penultimate step in the pathway of histidine biosynthesis. Oxidation of the alcohol group on the side chain gives the acid group forming histidine. Histidinol has also been used as an inhibitor of protein synthesis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The penultimate step in the pathway of histidine biosynthesis. Oxidation of the alcohol group on the side chain gives the acid group forming histidine. Histidinol has also been used as an inhibitor of protein synthesis.

Chemical Identity

Chemical Information

Molecular Formula
C6H11N3O
Molecular Weight
141.17 g/mol
CAS Registry No.
4836-52-6
IUPAC Name
(2S)-2-amino-3-(1H-imidazol-5-yl)propan-1-ol
InChIKey
ZQISRDCJNBUVMM-YFKPBYRVSA-N
SMILES
C1=C(NC=N1)C[C@@H](CO)N
MeSH Unique ID
D006641
Source
PubChem CID 165271

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

1 entry terms
  • Histidol

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under IMIDAZOLES 1975-90

MeSH Record

Previous Indexing

  • Amino Alcohols (1972-1974)
  • Imidazoles (1972-1974)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Histidinol. Medical Subject Headings (MeSH). 2026. Unique ID D006641. http://id.nlm.nih.gov/mesh/2026/D006641
  2. Histidinol. In: Wikidata. https://www.wikidata.org/wiki/Q27101817
  3. Histidinol. In: PubChem Compound. CID 165271. https://pubchem.ncbi.nlm.nih.gov/compound/165271