Chemicals and Drugs

Histone Deacetylase 3

A histone deacetylase that catalyzes the deacetylation of the core HISTONES (H2A, H2B,H3, and H4) as well as other cellular proteins. It functions in the CELL NUCLEUS as part of the nuclear-receptor corepressor complex to regulate the GENETIC TRANSCRIPTION of NUCLEAR RECEPTORS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A histone deacetylase that catalyzes the deacetylation of the core HISTONES (H2A, H2B,H3, and H4) as well as other cellular proteins. It functions in the CELL NUCLEUS as part of the nuclear-receptor corepressor complex to regulate the GENETIC TRANSCRIPTION of NUCLEAR RECEPTORS.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

1 entry terms
  • HDAC3 Enzyme

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2026 (2001)

MeSH Hierarchy

Tree Number

  1. D08.811w.277w.087w.520w.275

AMA Style

References

  1. National Library of Medicine. Histone Deacetylase 3. Medical Subject Headings (MeSH). 2026. Unique ID D000099186. http://id.nlm.nih.gov/mesh/2026/D000099186
  2. Histone Deacetylase 3. In: Wikidata. https://www.wikidata.org/wiki/Q21154358