Chemicals and Drugs

Histone Deacetylase Inhibitors

Compounds that inhibit HISTONE DEACETYLASES. This class of drugs may influence gene expression by increasing the level of acetylated HISTONES in specific CHROMATIN domains.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Compounds that inhibit HISTONE DEACETYLASES. This class of drugs may influence gene expression by increasing the level of acetylated HISTONES in specific CHROMATIN domains.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

9 entry terms
  • HDAC Inhibitor
  • HDAC Inhibitors
  • Histone Deacetylase Inhibitor
  • Deacetylase Inhibitor, Histone
  • Deacetylase Inhibitors, Histone
  • Inhibitor, HDAC
  • Inhibitor, Histone Deacetylase
  • Inhibitors, HDAC
  • Inhibitors, Histone Deacetylase

MeSH Record

Aspects Covered

22 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2010

MeSH Record

Previous Indexing

  • Histone Deacetylases/antagonists & inhibitors (1978-2009)

MeSH Hierarchy

Tree Number

  1. D27.505.519w.389w.360w

AMA Style

References

  1. National Library of Medicine. Histone Deacetylase Inhibitors. Medical Subject Headings (MeSH). 2026. Unique ID D056572. http://id.nlm.nih.gov/mesh/2026/D056572
  2. Histone Deacetylase Inhibitors. In: Wikipedia. https://en.wikipedia.org/wiki/Histone_deacetylase_inhibitor
  3. Histone Deacetylase Inhibitors. In: Wikidata. https://www.wikidata.org/wiki/Q3569101