Structured Summary
Abstract
Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these genes often results in homeotic transformations, in which one body structure replaces another. The proteins encoded by homeobox genes are called HOMEODOMAIN PROTEINS.
MeSH Record
Classification
Broader headings
Related Concepts
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See Also
MeSH Record
Synonyms
27 entry terms
- Genes, Homeo Box
- Genes, Homeobox
- Genes, Homeotic
- Homeotic Genes
- Hox Genes
- Gene, Homeo Box
- Gene, Homeobox
- Gene, Homeotic
- Gene, Hox
- Genes, Hox
- Homeo Box Gene
- Homeo Box Genes
- Homeobox Gene
- Homeotic Gene
- Hox Gene
- Homeo Box
- Homeo Box Sequence
- Homeo Boxes
- Homeobox
- Homeobox Sequence
- Homeoboxes
- Sequence, Homeo Box
- Homeo Box Sequences
- Homeobox Sequences
- Sequence, Homeobox
- Sequences, Homeo Box
- Sequences, Homeobox
MeSH Record
Aspects Covered
5 allowable subheadings
Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.
MeSH Record
History Note
95; was GENES, HOMEO BOX 1987-94
MeSH Record
Previous Indexing
- Alleles (1968-1975)
- Drosophila Melanogaster (1972-1986)
- Genes, Structural (1983-1986)
- Morphogenesis (1983-1986)
MeSH Hierarchy
Tree Number
MeSH Record
NLM Classification
QU 470
AMA Style
References
- National Library of Medicine. Homeobox Genes. Medical Subject Headings (MeSH). 2026. Unique ID D005801. http://id.nlm.nih.gov/mesh/2026/D005801
- Homeobox Genes. In: Wikipedia. https://en.wikipedia.org/wiki/Homeobox
- Homeobox Genes. In: Wikidata. https://www.wikidata.org/wiki/Q898769