Structured Summary
Abstract
A homeobox-containing transcription factor that functions in heart development. Mutations in the NKX2-5 gene are associated with ATRIAL SEPTAL DEFECTS and TETRALOGY OF FALLOT.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
14 entry terms
- Cardiac-Specific Homeobox Protein
- Homeobox Protein Csx-Nkx2.5
- Homeobox Transcription Factor Csx-Nkx2-5
- NK2 Homeobox 5 Protein
- Transcription Factor Nkx-2.5
- Cardiac Specific Homeobox Protein
- Csx-Nkx2.5, Homeobox Protein
- Homeobox Protein Csx Nkx2.5
- Homeobox Protein Nkx 2.5
- Homeobox Protein, Cardiac-Specific
- Homeobox Transcription Factor Csx Nkx2 5
- Nkx-2.5, Homeobox Protein
- Nkx-2.5, Transcription Factor
- Transcription Factor Nkx 2.5
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017
MeSH Record
Previous Indexing
- Homeodomain Proteins (1995-2016)
- Transcription Factors (1995-2016)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Homeobox Protein Nkx-2.5. Medical Subject Headings (MeSH). 2026. Unique ID D000072576. http://id.nlm.nih.gov/mesh/2026/D000072576
- Homeobox Protein Nkx-2.5. In: Wikidata. https://www.wikidata.org/wiki/Q24783592