Chemicals and Drugs

Host Cell Factor C1

A cellular transcriptional coactivator that contains N-terminal KELCH REPEATS and N- and C-terminal FIBRONECTIN TYPE III DOMAINS. It functions as a transcription factor for a number of genes and in the assembly of IMMEDIATE-EARLY PROTEINS of the HERPES SIMPLEX VIRUS. Mutations in the HCFC1 gene are associated with cases of X-LINKED MENTAL RETARDATION.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A cellular transcriptional coactivator that contains N-terminal KELCH REPEATS and N- and C-terminal FIBRONECTIN TYPE III DOMAINS. It functions as a transcription factor for a number of genes and in the assembly of IMMEDIATE-EARLY PROTEINS of the HERPES SIMPLEX VIRUS. Mutations in the HCFC1 gene are associated with cases of X-LINKED MENTAL RETARDATION.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

3 entry terms
  • C1 Host Cell Factor
  • Cell Proliferation Factor HCF
  • HCFC1 Protein

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1995)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.660w.478
  2. D12.776w.930w.325

AMA Style

References

  1. National Library of Medicine. Host Cell Factor C1. Medical Subject Headings (MeSH). 2026. Unique ID D051863. http://id.nlm.nih.gov/mesh/2026/D051863
  2. Host Cell Factor C1. In: Wikidata. https://www.wikidata.org/wiki/Q21130029