Diseases

Hypereosinophilic Syndrome

A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. There is a massive increase in the number of EOSINOPHILS in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. There is a massive increase in the number of EOSINOPHILS in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs.

MeSH Record

Classification

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MeSH Record

Synonyms

19 entry terms
  • Hypereosinophilic Syndromes
  • Syndrome, Hypereosinophilic
  • Syndromes, Hypereosinophilic
  • Endocarditis, Loeffler
  • Endocarditis, Loeffler's
  • Hypereosinophilic Syndrome, Idiopathic
  • Idiopathic Hypereosinophilic Syndrome
  • Leukemia, Eosinophilic
  • Loeffler Endocarditis
  • Loeffler's Endocarditis
  • Endocarditis, Loefflers
  • Eosinophilic Leukemia
  • Eosinophilic Leukemias
  • Hypereosinophilic Syndromes, Idiopathic
  • Idiopathic Hypereosinophilic Syndromes
  • Leukemias, Eosinophilic
  • Loefflers Endocarditis
  • Syndrome, Idiopathic Hypereosinophilic
  • Syndromes, Idiopathic Hypereosinophilic

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

do not confuse entry term LOEFFLER'S ENDOCARDITIS with LOEFFLER SYNDROME see PULMONARY EOSINOPHILIA

MeSH Record

History Note

94

MeSH Record

Previous Indexing

  • Eosinophilia (1966-1993)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Hypereosinophilic Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D017681. http://id.nlm.nih.gov/mesh/2026/D017681
  2. Hypereosinophilic Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Hypereosinophilic_syndrome
  3. Hypereosinophilic Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q2551272