Diseases

Hypoaldosteronism

A congenital or acquired condition of insufficient production of ALDOSTERONE by the ADRENAL CORTEX leading to diminished aldosterone-mediated synthesis of Na(+)-K(+)-EXCHANGING ATPASE in renal tubular cells. Clinical symptoms include HYPERKALEMIA, sodium-wasting, HYPOTENSION, and sometimes metabolic ACIDOSIS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A congenital or acquired condition of insufficient production of ALDOSTERONE by the ADRENAL CORTEX leading to diminished aldosterone-mediated synthesis of Na(+)-K(+)-EXCHANGING ATPASE in renal tubular cells. Clinical symptoms include HYPERKALEMIA, sodium-wasting, HYPOTENSION, and sometimes metabolic ACIDOSIS.

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Classification

Broader headings

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See Also

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Synonyms

5 entry terms
  • Acidosis, Renal Tubular Type IV
  • Hypoaldosteronism, Hyporeninemic
  • Hyporeninemic Hypoaldosteronism
  • Renal Tubular Acidosis, Type IV
  • Type IV Renal Tubular Acidosis

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

do not confuse with HYPERALDOSTERONISM or PSEUDOHYPOALDOSTERONISM

MeSH Record

History Note

88

MeSH Record

Previous Indexing

  • Adrenal Gland Hypofunction (1966-1987)
  • Aldosterone (1966-1987)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Hypoaldosteronism. Medical Subject Headings (MeSH). 2026. Unique ID D006994. http://id.nlm.nih.gov/mesh/2026/D006994
  2. Hypoaldosteronism. In: Wikipedia. https://en.wikipedia.org/wiki/Hypoaldosteronism
  3. Hypoaldosteronism. In: Wikidata. https://www.wikidata.org/wiki/Q2378552