Structured Summary
Abstract
A formulation for presenting an antigen to induce specific immunologic responses. It consists of an assembly of antigens in multimeric form. The assembly is attached to a matrix with a built-in adjuvant, saponin. ISCOMs induce strong serum antibody responses, and are used as highly immunogenic forms of subunit vaccines.
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Classification
Broader headings
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Drug Class
Pharmacological Action
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See Also
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Synonyms
6 entry terms
- ISCOM
- Immuno-Stimulating Complexes
- Immunostimulating Complexes
- Complexes, Immuno-Stimulating
- Complexes, Immunostimulating
- Immuno Stimulating Complexes
MeSH Record
Aspects Covered
22 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
Indexing Annotation
coord IM with specific type of vaccine (IM or NIM)
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History Note
92
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Previous Indexing
- Adjuvants, Immunologic (1985-1991)
- Viral Vaccines (1985-1991)
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Tree Number
AMA Style
References
- National Library of Medicine. ISCOMs. Medical Subject Headings (MeSH). 2026. Unique ID D016882. http://id.nlm.nih.gov/mesh/2026/D016882
- ISCOMs. In: Wikipedia. https://en.wikipedia.org/wiki/ISCOM
- ISCOMs. In: Wikidata. https://www.wikidata.org/wiki/Q5973803