Chemicals and Drugs

Iduronate Sulfatase

An enzyme that specifically cleaves the ester sulfate of iduronic acid. Its deficiency has been demonstrated in Hunter's syndrome, which is characterized by an excess of dermatan sulfate and heparan sulfate. EC 3.1.6.13.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that specifically cleaves the ester sulfate of iduronic acid. Its deficiency has been demonstrated in Hunter's syndrome, which is characterized by an excess of dermatan sulfate and heparan sulfate. EC 3.1.6.13.

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

Loading graph…

Drag nodes to rearrange; hover to trace links; click a node to open its page.

MeSH Record

See Also

MeSH Record

Synonyms

11 entry terms
  • Hunter Corrective Factor
  • Iduronate Sulfate Sulfatase
  • Iduronatesulfate Sulfohydrolase
  • Sulfoiduronate Sulfatase
  • Corrective Factor, Hunter
  • Factor, Hunter Corrective
  • Sulfatase, Iduronate
  • Sulfatase, Iduronate Sulfate
  • Sulfatase, Sulfoiduronate
  • Sulfate Sulfatase, Iduronate
  • Sulfohydrolase, Iduronatesulfate

MeSH Record

Aspects Covered

28 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

91(76); was see under SULFATASES 1976-90

MeSH Record

Previous Indexing

  • Iduronic Acid (1975)
  • Sulfatases (1972-1975)
  • Uronic Acids (1972-1975)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Iduronate Sulfatase. Medical Subject Headings (MeSH). 2026. Unique ID D007066. http://id.nlm.nih.gov/mesh/2026/D007066
  2. Iduronate Sulfatase. In: Wikipedia. https://en.wikipedia.org/wiki/Iduronate-2-sulfatase
  3. Iduronate Sulfatase. In: Wikidata. https://www.wikidata.org/wiki/Q76853342