Chemicals and Drugs

Immunoglobulin Constant Regions

The domains of the immunoglobulin molecules that are invariable in their amino acid sequence within any class or subclass of immunoglobulin. They confer biological as well as structural functions to immunoglobulins. One each on both the light chains and the heavy chains comprises the C-terminus half of the IMMUNOGLOBULIN FAB FRAGMENT and two or three of them make up the rest of the heavy chains (all of the IMMUNOGLOBULIN FC FRAGMENT)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The domains of the immunoglobulin molecules that are invariable in their amino acid sequence within any class or subclass of immunoglobulin. They confer biological as well as structural functions to immunoglobulins. One each on both the light chains and the heavy chains comprises the C-terminus half of the IMMUNOGLOBULIN FAB FRAGMENT and two or three of them make up the rest of the heavy chains (all of the IMMUNOGLOBULIN FC FRAGMENT)

MeSH Record

Classification

Broader headings

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Drug Class

Pharmacological Action

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See Also

MeSH Record

Synonyms

7 entry terms
  • Constant Region, Ig
  • Ig Constant Regions
  • Immunoglobulin Constant Region
  • Constant Region, Immunoglobulin
  • Constant Regions, Ig
  • Constant Regions, Immunoglobulin
  • Regions, Ig Constant

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006 (1979)

MeSH Record

Previous Indexing

  • Gamma Globulins (1966-1971)
  • Immunoglobulin Allotypes (1975-1978)
  • Immunoglobulins (1972-1978)
  • Immunoglobulins, Fc (1973)
  • specific immunoglobulin fragment (1973-1978)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.124w.486.485.538
  2. D12.776w.124w.790.651.538
  3. D12.776w.377w.715.548.538

AMA Style

References

  1. National Library of Medicine. Immunoglobulin Constant Regions. Medical Subject Headings (MeSH). 2026. Unique ID D007127. http://id.nlm.nih.gov/mesh/2026/D007127
  2. Immunoglobulin Constant Regions. In: Wikidata. https://www.wikidata.org/wiki/Q77201342