Structured Summary
Abstract
Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN GENES. The heavy and light immunoglobulin genes are present as gene segments in the germline cells. The completed genes are created when the segments are shuffled and assembled (B-LYMPHOCYTE GENE REARRANGEMENT) during B-LYMPHOCYTE maturation. The gene segments of the human light and heavy chain germline genes are symbolized V (variable), J (joining) and C (constant). The heavy chain germline genes have an additional segment D (diversity).
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Synonyms
7 entry terms
- Genes, Ig
- Genes, Immunoglobulin
- Gene, Ig
- Gene, Immunoglobulin
- Ig Gene
- Ig Genes
- Immunoglobulin Gene
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Aspects Covered
5 allowable subheadings
Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.
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History Note
88
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Previous Indexing
- Genes, Structural (1972-1987)
- Immunoglobulins (1972-1987)
- specific immunoglobulin chain or region (1975-1987)
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NLM Classification
QW 601
AMA Style
References
- National Library of Medicine. Immunoglobulin Genes. Medical Subject Headings (MeSH). 2026. Unique ID D005803. http://id.nlm.nih.gov/mesh/2026/D005803
- Immunoglobulin Genes. In: Wikidata. https://www.wikidata.org/wiki/Q70688789