Structured Summary
Abstract
Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.
MeSH Record
Classification
Related Concepts
Knowledge Graph
Drag nodes to rearrange; hover to trace links; click a node to open its page.
Drug Class
Pharmacological Action
MeSH Record
See Also
MeSH Record
Synonyms
7 entry terms
- Idiotypes, Immunoglobulin
- Ig Idiotypes
- Idiotype, Ig
- Idiotype, Immunoglobulin
- Idiotypes, Ig
- Ig Idiotype
- Immunoglobulin Idiotype
MeSH Record
Aspects Covered
23 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
79
MeSH Record
Previous Indexing
- Anti-Antibodies (1966-1969)
- Antibody Specificity (1970-1978)
- Antigenic Determinants (1970-1978)
- Binding Sites, Antibody (1973-1978)
MeSH Hierarchy
Tree Numbers
MeSH Record
NLM Classification
QW 601
AMA Style
References
- National Library of Medicine. Immunoglobulin Idiotypes. Medical Subject Headings (MeSH). 2026. Unique ID D007130. http://id.nlm.nih.gov/mesh/2026/D007130
- Immunoglobulin Idiotypes. In: Wikipedia. https://en.wikipedia.org/wiki/Idiotype
- Immunoglobulin Idiotypes. In: Wikidata. https://www.wikidata.org/wiki/Q1047644